Keywords
Contaminants in the Urban Environment series
Perfluoroalkyl sustances
SS631
Perfluoroalkyl sustances
SS631
How to Cite
Rodriguez-Jorquera, Ignacio A., and Gurpal S. Toor. 2015. “Contaminants in the Urban Environment: Perfluoroalkyl Substances: SL418/SS631, 3/2015”. EDIS 2015 (3). Gainesville, FL:6. https://doi.org/10.32473/edis-ss631-2015.
Abstract
Perfluoroalkyl substances (PFASs) or perfluorochemicals (PFCs) are the most widespread and persistent manmade chemicals on earth. Common products that contain PFASs are Teflon pans, non-stick cookware, rain/waterproof jackets (like Gore-Tex), fire-fighting foams, food packaging, carpets, and furniture fabrics. PFASs stay in the environment for a long period of time, which means they can accumulate in organisms to levels that cause harmful effects. This 6-page fact sheet discusses the occurrence, use, exposure, and potential harmful effects of PFASs to humans and the environment, and suggests ways to reduce your exposure to PFSAs. Written by Ignacio A. Rodriguez-Jorquera and Gurpal S. Toor, and published by the UF Department of Soil and Water Science, March 2015. (Photos: Thinkstock.com)
SL418/SS631: Contaminants in the Urban Environment: Perfluoroalkyl Substances (ufl.edu)
References
Ahrens, L. 2011. "Polyfluoroalkyl compounds in the aquatic environment: a review of their occurrence and fate." Journal of Environmental Monitoring 13: 20-31. https://doi.org/10.1039/C0EM00373E
Du, Y., X. Shi, C. Liu, K. Yu, and B. Zhou. 2009. "Chronic effects of water-borne PFOS exposure on growth, survival and hepatotoxicity in zebrafish: A partial life-cycle test." Chemosphere 74: 723-729. https://doi.org/10.1016/j.chemosphere.2008.09.075
Eriksen, K. T., O. Raaschou-Nielsen, J. K. McLaughlin, L. Lipworth, A. Tjønneland, K. Overvad, and M. Sørensen. 2013. "Association between Plasma PFOA and PFOS Levels and Total Cholesterol in a Middle-Aged Danish Population." PloS ONE 8, e56969. https://doi.org/10.1371/journal.pone.0056969
Fromme, H., S. A. Tittlemier, W. Völkel, M. Wilhelm, and D. Twardella. 2009. "Perfluorinated compounds-Exposure assessment for the general population in western countries." International Journal of Hygiene and Environmental Health 212: 239-270. https://doi.org/10.1016/j.ijheh.2008.04.007
Gladysz, J., and M. Jurisch. 2012. "Structural, Physical, and Chemical Properties of Fluorous Compounds," in Fluorous Chemistry, edited by I. T. Horváth. Springer Berlin Heidelberg, pp. 1-23. https://doi.org/10.1007/128_2011_282
Hong, A. C., C. J. Young, M. D. Hurley, T. J. Wallington, and S. A. Mabury. 2013. "Perfluorotributylamine: A novel long‐lived greenhouse gas." Geophysical Research Letters 40(22): 6010-6015. https://doi.org/10.1002/2013GL058010
Houde, M., A. O. De Silva, D. C. G. Muir, and R. J. Letcher. 2011. "Monitoring of Perfluorinated Compounds in Aquatic Biota: An Updated Review." Environmental Science & Technology 45: 7962-7973. https://doi.org/10.1021/es104326w
Jacquet, N., M. A. Maire, Y. Landkocz, and P. Vasseur. 2012. "Carcinogenic potency of perfluorooctane sulfonate (PFOS) on Syrian hamster embryo (SHE) cells." Archives of Toxicology 86: 305-314. https://doi.org/10.1007/s00204-011-0752-8
Kannan, K., S. Corsolini, J. Falandysz, G. Fillmann, K. S. Kumar, B. G. Loganathan, M. A. Mohd, J. Olivero, N. V. Wouwe, J. H. Yang,, and K. M. Aldous. 2004. "Perfluorooctanesulfonate and Related Fluorochemicals in Human Blood from Several Countries." Environmental Science & Technology 38: 4489-4495. https://doi.org/10.1021/es0493446
Kato, K., A. M. Calafat, and L. L. Needham. 2009. "Polyfluoroalkyl chemicals in house dust." Environ Res 109: 518-523. https://doi.org/10.1016/j.envres.2009.01.005
Kudo, N., and Y. Kawashima. 2003. "Toxicity and Toxicokinetics of Perfluorooctanoic Acid in Humans and Animals." The Journal of Toxicological Sciences 28: 49-57. https://doi.org/10.2131/jts.28.49
Liu, C., Y. Du, and B. Zhou. 2007. "Evaluation of estrogenic activities and mechanism of action of perfluorinated chemicals determined by vitellogenin induction in primary cultured tilapia hepatocytes." Aquatic Toxicology 85: 267-277. https://doi.org/10.1016/j.aquatox.2007.09.009
Mariussen, E. 2012. "Neurotoxic effects of perfluoroalkylated compounds: mechanisms of action and environmental relevance." Archives of Toxicology 86: 1349-1367. https://doi.org/10.1007/s00204-012-0822-6
Oakes, K. D., P. K. Sibley, K. R. Solomon, S. A. Mabury, and G. J. Van Der Kraak. 2004. "Impact of perfluorooctanoic acid on fathead minnow (Pimephales promelas) fatty acyl-coa oxidase activity, circulating steroids, and reproduction in outdoor microcosms." Environmental Toxicology and Chemistry 23: 1912-1919. https://doi.org/10.1897/03-190
Olsen, G. W., J. M. Burris, D. J. Ehresman, J. W. Froehlich, A. M. Seacat, J. L. Butenhoff, and L. R. Zobel. 2007. "Half-Life of Serum Elimination of Perfluorooctanesulfonate, Perfluorohexanesulfonate, and Perfluorooctanoate in Retired Fluorochemical Production Workers." Environmental Health Perspectives 115: 1298-1305. https://doi.org/10.1289/ehp.10009
Olsen, G. W., J. M. Burris, J. H. Mandel, and L. R. Zobel. 1999. "Serum Perfluorooctane Sulfonate and Hepatic and Lipid Clinical Chemistry Tests in Fluorochemical Production Employees." Journal of Occupational and Environmental Medicine 41: 799-806.
ttps://doi.org/10.1097/00043764-199909000-00012
Stahl, T., Mattern, D., Brunn, H. 2011. "Toxicology of perfluorinated compounds." Environmental Sciences Europe 23:38, 1-52. https://doi.org/10.1186/2190-4715-23-38
US EPA. 2017. Technical Fact Sheet-Perfluorooctane Sulfonate (PFOS) and Perfluorooctanoic Acid (PFOA). Available at: https://www.epa.gov/sites/production/files/2017-12/documents/ffrrofactsheet_contaminants_pfos_pfoa_11-20-17_508_0.pdf. Accessed on 30 April 2018.
Wang, Y., W. J. Rogan, P. C. Chen, G.-W. Lien, H. Y. Chen, Y. C. Tseng, M. P. Longnecker, and S. L. Wang. 2014. "Association between maternal serum perfluoroalkyl substances during pregnancy and maternal and cord thyroid hormones: Taiwan maternal and infant cohort study." Environmental Health Perspectives 122: 529-534. https://doi.org/10.1289/ehp.1306925
Yang, Q., M. Abedi-Valugerdi, Y. Xie, X.-Y. Zhao, G. Möller, B. Dean Nelson, and J. W. DePierre. 2002. "Potent suppression of the adaptive immune response in mice upon dietary exposure to the potent peroxisome proliferator, perfluorooctanoic acid." International Immunopharmacology 2: 389-397. https://doi.org/10.1016/S1567-5769(01)00164-3
Du, Y., X. Shi, C. Liu, K. Yu, and B. Zhou. 2009. "Chronic effects of water-borne PFOS exposure on growth, survival and hepatotoxicity in zebrafish: A partial life-cycle test." Chemosphere 74: 723-729. https://doi.org/10.1016/j.chemosphere.2008.09.075
Eriksen, K. T., O. Raaschou-Nielsen, J. K. McLaughlin, L. Lipworth, A. Tjønneland, K. Overvad, and M. Sørensen. 2013. "Association between Plasma PFOA and PFOS Levels and Total Cholesterol in a Middle-Aged Danish Population." PloS ONE 8, e56969. https://doi.org/10.1371/journal.pone.0056969
Fromme, H., S. A. Tittlemier, W. Völkel, M. Wilhelm, and D. Twardella. 2009. "Perfluorinated compounds-Exposure assessment for the general population in western countries." International Journal of Hygiene and Environmental Health 212: 239-270. https://doi.org/10.1016/j.ijheh.2008.04.007
Gladysz, J., and M. Jurisch. 2012. "Structural, Physical, and Chemical Properties of Fluorous Compounds," in Fluorous Chemistry, edited by I. T. Horváth. Springer Berlin Heidelberg, pp. 1-23. https://doi.org/10.1007/128_2011_282
Hong, A. C., C. J. Young, M. D. Hurley, T. J. Wallington, and S. A. Mabury. 2013. "Perfluorotributylamine: A novel long‐lived greenhouse gas." Geophysical Research Letters 40(22): 6010-6015. https://doi.org/10.1002/2013GL058010
Houde, M., A. O. De Silva, D. C. G. Muir, and R. J. Letcher. 2011. "Monitoring of Perfluorinated Compounds in Aquatic Biota: An Updated Review." Environmental Science & Technology 45: 7962-7973. https://doi.org/10.1021/es104326w
Jacquet, N., M. A. Maire, Y. Landkocz, and P. Vasseur. 2012. "Carcinogenic potency of perfluorooctane sulfonate (PFOS) on Syrian hamster embryo (SHE) cells." Archives of Toxicology 86: 305-314. https://doi.org/10.1007/s00204-011-0752-8
Kannan, K., S. Corsolini, J. Falandysz, G. Fillmann, K. S. Kumar, B. G. Loganathan, M. A. Mohd, J. Olivero, N. V. Wouwe, J. H. Yang,, and K. M. Aldous. 2004. "Perfluorooctanesulfonate and Related Fluorochemicals in Human Blood from Several Countries." Environmental Science & Technology 38: 4489-4495. https://doi.org/10.1021/es0493446
Kato, K., A. M. Calafat, and L. L. Needham. 2009. "Polyfluoroalkyl chemicals in house dust." Environ Res 109: 518-523. https://doi.org/10.1016/j.envres.2009.01.005
Kudo, N., and Y. Kawashima. 2003. "Toxicity and Toxicokinetics of Perfluorooctanoic Acid in Humans and Animals." The Journal of Toxicological Sciences 28: 49-57. https://doi.org/10.2131/jts.28.49
Liu, C., Y. Du, and B. Zhou. 2007. "Evaluation of estrogenic activities and mechanism of action of perfluorinated chemicals determined by vitellogenin induction in primary cultured tilapia hepatocytes." Aquatic Toxicology 85: 267-277. https://doi.org/10.1016/j.aquatox.2007.09.009
Mariussen, E. 2012. "Neurotoxic effects of perfluoroalkylated compounds: mechanisms of action and environmental relevance." Archives of Toxicology 86: 1349-1367. https://doi.org/10.1007/s00204-012-0822-6
Oakes, K. D., P. K. Sibley, K. R. Solomon, S. A. Mabury, and G. J. Van Der Kraak. 2004. "Impact of perfluorooctanoic acid on fathead minnow (Pimephales promelas) fatty acyl-coa oxidase activity, circulating steroids, and reproduction in outdoor microcosms." Environmental Toxicology and Chemistry 23: 1912-1919. https://doi.org/10.1897/03-190
Olsen, G. W., J. M. Burris, D. J. Ehresman, J. W. Froehlich, A. M. Seacat, J. L. Butenhoff, and L. R. Zobel. 2007. "Half-Life of Serum Elimination of Perfluorooctanesulfonate, Perfluorohexanesulfonate, and Perfluorooctanoate in Retired Fluorochemical Production Workers." Environmental Health Perspectives 115: 1298-1305. https://doi.org/10.1289/ehp.10009
Olsen, G. W., J. M. Burris, J. H. Mandel, and L. R. Zobel. 1999. "Serum Perfluorooctane Sulfonate and Hepatic and Lipid Clinical Chemistry Tests in Fluorochemical Production Employees." Journal of Occupational and Environmental Medicine 41: 799-806.
ttps://doi.org/10.1097/00043764-199909000-00012
Stahl, T., Mattern, D., Brunn, H. 2011. "Toxicology of perfluorinated compounds." Environmental Sciences Europe 23:38, 1-52. https://doi.org/10.1186/2190-4715-23-38
US EPA. 2017. Technical Fact Sheet-Perfluorooctane Sulfonate (PFOS) and Perfluorooctanoic Acid (PFOA). Available at: https://www.epa.gov/sites/production/files/2017-12/documents/ffrrofactsheet_contaminants_pfos_pfoa_11-20-17_508_0.pdf. Accessed on 30 April 2018.
Wang, Y., W. J. Rogan, P. C. Chen, G.-W. Lien, H. Y. Chen, Y. C. Tseng, M. P. Longnecker, and S. L. Wang. 2014. "Association between maternal serum perfluoroalkyl substances during pregnancy and maternal and cord thyroid hormones: Taiwan maternal and infant cohort study." Environmental Health Perspectives 122: 529-534. https://doi.org/10.1289/ehp.1306925
Yang, Q., M. Abedi-Valugerdi, Y. Xie, X.-Y. Zhao, G. Möller, B. Dean Nelson, and J. W. DePierre. 2002. "Potent suppression of the adaptive immune response in mice upon dietary exposure to the potent peroxisome proliferator, perfluorooctanoic acid." International Immunopharmacology 2: 389-397. https://doi.org/10.1016/S1567-5769(01)00164-3