Drug Transport and Pharmacokinetics for Chemical Engineers

Authors

  • Laurent Simon New Jersey Institute of Technology
  • Kumud Kanneganti New Jersey Institute of Technology
  • Kwang Seok Kim New Jersey Institute of Technology

Abstract

Experiments in continuous-stirred vessels were proposed to introduce methods in pharmacokinetics and drug transport to chemical engineering students. The activities can be incorporated into the curriculum to illustrate fundamentals learned in the classroom. An appreciation for the role of pharmacokinetics in drug discovery will also be gained through this process. Intravenous bolus injections and continuous infusions of a medicament were demonstrated by manipulation of stream flow rates and changes in the amount of potassium permanganate added to a beaker.

Author Biographies

Laurent Simon, New Jersey Institute of Technology

Laurent Simon is an associate professor of chemical engineering and the associate director
of the Pharmaceutical Engineering Program at the New Jersey Institute of Technology. He received his Ph.D. in chemical engineering from Colorado State University in 2001. His research and teaching interests involve modeling, analysis, and control of drug-delivery systems. He is the author of Laboratory Online, available at <http://laurentsimon.com/simon/>, a series of educational and interactive modules to enhance engineering knowledge in drugdelivery technologies and underlying engineering principles.

Kumud Kanneganti, New Jersey Institute of Technology

Kumud Kanneganti is pursuing a Master’s degree in the Otto H. York Department of Chemical, Biological, and Pharmaceutical Engineering. He received a B. Tech. degree in chemical engineering from Nirma University of Science and Technology (NU), India. His research focus is in the design of drug delivery strategies using well-stirred vessel experiments.

Kwang Seok Kim, New Jersey Institute of Technology

Kwang Seok Kim is a Ph.D. student in the Otto H. York Department of Chemical, Biological, and Pharmaceutical Engineering. He received his B.S. (2004) and M.S. (2006) degrees in chemical engineering from the University of Seoul, Korea. His research interests include the design and control of drug delivery systems.

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Published

2010-09-01

Issue

Vol. 44 No. 4 (2010): Fall 2010

Section

Manuscripts