Drug Transport and Pharmacokinetics for Chemical Engineers
Abstract
Experiments in continuous-stirred vessels were proposed to introduce methods in pharmacokinetics and drug transport to chemical engineering students. The activities can be incorporated into the curriculum to illustrate fundamentals learned in the classroom. An appreciation for the role of pharmacokinetics in drug discovery will also be gained through this process. Intravenous bolus injections and continuous infusions of a medicament were demonstrated by manipulation of stream flow rates and changes in the amount of potassium permanganate added to a beaker.