Nematicidal Activity of α-Chaconine: Effect of Hydrogen-ion Concentration
Abstract
[alpha]-Chaconine, a steroid-glycoalkaloid from Solanum tuberosum L., was increasingly more toxic to a free-living nematode, Panagrellus redivivus, with decreasing acidity from about pH 5 to 7. A study of the toxicity to adult nematodes at three concentrations of [alpha]-chaconine in buffer from pH 4 to 7.5 indicated that the free base is the nematicidal form of the compound. The median effective doses (ED[sub5][sub0]) of [alpha]-chaconine to inhibit the motility of P. redivivus were estimated as 85 [mu]g/ml at pH 6.7, 170 [mu]g/ml at pH 6.5, and 340 [mu]g/ml at pH 6.2. Key Words: Nematicide, Steroid-glycoalkaloid, [alpha]-Chaconine, Toxicity, Hydrogen-ion concentration.Downloads
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