Chemosterilant Activity of 75 Compounds against the Tobacco Budworm

Authors

  • D. A. Wolfenbarger
  • Aliud Cantu
  • A. A. Guerra
  • J. G. Pomonis
  • S. H. Robinson
  • R. D. Garcia

Abstract

Thiotepa, a triaziridinyl phosphinic sulfide, was the most effective of 75 compounds evaluated as chemosterilants against the tobacco budworm, Heliothis virescens (F.). Thiotepa was applied topically to adults, and it was 4 times more effective against males than females. Females treated with thiotepa and placed in competition with untreated females were competitive at 4, 2, and 1:1 ratios; males handled similarly were competitive at a 1:1 ratio only. However, males treated with thiotepa and untreated males transferred eupyrene sperm equally well to untreated females. Two heteroaromatic aziridines, tretamine (an s-triazine) and 2,6-bis(1-aziridinyl)-pyrazine (a pyrazine), sterilized both sexes when applied topically. The same dose of tretamine sterilized both sexes without inhibiting sexual competitiveness. Pairs of adults from larvae that had been injected or fed with the nonaziridinyl methylenedioxy compound, 5-acetyl-5-[4,5-(methylenedioxy)-2-propylbenzyl]-4,5-dihydrofur-2(3H)-anone, were sterile; pairs composed of treated moths and untreated moths were not.

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Published

1974-09-01

Issue

Section

Literature Review Articles