CryptoDNA: A Machine Learning Paradigm for DDoS Detection in Healthcare IoT, Inspired by Cryptojacking prevention Models

Authors

  • Zag ElSayed University of Cincinnati - Children's Hospital
  • Nelly Elsayed University of Cincinnati
  • Ahmed Abdelgawad Central Michigan University

DOI:

https://doi.org/10.32473/flairs.38.1.138680

Keywords:

CryptoDNA, AI, Machine Learning, Healthcare, IoT, Internet of Things, DDoS, Cryptojacking, Artificial Neural Network, Network, traffic, Cybersecurity, anomaly detection, infrastructure, IoM, Biomedical, DoS, threats, Framework, model, zero-day, attack, business, Information Systems

Abstract

The rapid integration of the Internet of Things (IoT) and Internet of Medical (IoM) devices in the healthcare industry has markedly improved patient care and hospital operations but has concurrently brought substantial risks. Distributed Denial-of-Service (DDoS) attacks present significant dangers, jeopardizing operational stability and patient safety. This study introduces CryptoDNA, an innovative machine learning detection framework influenced by cryptojacking detection methods, designed to identify and alleviate DDoS attacks in healthcare IoT settings. The proposed approach relies on behavioral analytics, including atypical resource usage and network activity patterns. Key features derived from cryptojacking-inspired methodologies include entropy-based analysis of traffic, time-series monitoring of device performance, and dynamic anomaly detection. A lightweight architecture ensures inter-compatibility with resource-constrained IoT devices while maintaining high detection accuracy. The proposed architecture and model were tested in real-world and synthetic datasets to demonstrate the model's superior performance, achieving over 96% accuracy with minimal computational overhead. Comparative analysis reveals its resilience against emerging attack vectors and scalability across diverse device ecosystems. By bridging principles from cryptojacking and DDoS detection, CryptoDNA offers a robust, innovative solution to fortify the healthcare IoT landscape against evolving cyber threats and highlights the potential of interdisciplinary approaches in adaptive cybersecurity defense mechanisms for critical healthcare infrastructures

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Published

14-05-2025

How to Cite

ElSayed, Z., Elsayed, N., & Abdelgawad, A. (2025). CryptoDNA: A Machine Learning Paradigm for DDoS Detection in Healthcare IoT, Inspired by Cryptojacking prevention Models. The International FLAIRS Conference Proceedings, 38(1). https://doi.org/10.32473/flairs.38.1.138680

Issue

Section

Special Track: AI in Healthcare Informatics