An Evidence-based Practice Project to Manage Cancer-related Fatigue in Adults Undergoing Chemotherapy

Abstract

This evidence-based practice project examined whether walking interventions reduce fatigue in adult cancer patients undergoing chemotherapy. A structured literature review was executed using Cumulative Index to Nursing and Allied Health (CINHAL), ProQuest Nursing and Allied Health, PubMed, and Cochrane Reviews. Seven peer-reviewed studies were included, consisting of a randomized control trial, systematic reviews with meta-analyses, observational studies, and a clinical practice guideline. The articles addressed the following PICO question: In adult cancer patients receiving chemotherapy (P), how does walking exercise interventions (I), compared to no standardized walking intervention (C), affect fatigue (O)? Walking interventions varied in intensity, duration, and structure, yet all supported walking as a safe, low-cost strategy that improves fatigue. Although variability in fatigue measures and program design existed, most studies reported reduced fatigue scores in walking groups. This project supports walking as a feasible nurse-led intervention that can be applied across inpatient, outpatient, and home care settings. Walking exercise interventions offer a practical and equitable approach for improving the quality of life in cancer patients and it aligns with the goals of holistic nursing care.